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This year’s list of biotech companies reflects the evolving impact of AI, a growing interest in cutting-edge research tools for single-cell analysis and spatial proteomics, and clinical advances for novel drug candidates that promise more convenient and effective treatment for conditions impacting millions of Americans. AlzPath’s highly sensitive blood test can detect signs of Alzheimer’s disease before symptoms develop—and in time to potentially benefit from new treatments. Genomic sequencing specialist GeneDx is helping parents discover and treat hundreds of rare diseases in newborns. 10x Genomics and Syncell streamline cutting-edge analytics for life science research,…

We’re more than half a decade removed from pandemic lockdowns—when remote work profoundly upended the 9-to-5—yet the preference for workday flexibility endures, a new report shows. According to the recently released ninth annual State of Hybrid Work report from Owl Labs, a video conference tech company, 65% of workers are interested in a concept the report refers to as “microshifting”: “structured flexibility with short, nonlinear work blocks matched to your energy, duties, or productivity.” In other words: breaking up your work shift into a bunch of tiny ones. Perhaps you log on at 6 a.m. to get a head start, then take a break for a midmorning Pilates class befo…

A consumer advocacy group filed a lawsuit this week to block insurers from charging California customers for $500 million in costs associated with the deadly Los Angeles fires. California’s insurance commission in February ordered insurers doing business in California to provide $1 billion to the FAIR Plan, the state’s insurer of last resort, to help it pay out claims related to the L.A. wildfires. The order allows insurers to recoup half the cost from its policyholders in the form of a onetime fee. The commissioner must approve the costs. The lawsuit, filed by Consumer Watchdog in Los Angeles, alleges Insurance Commissioner Ricardo Lara overstepped his authority …

Pharrell Williams has high hopes for the Met Gala, the first to focus exclusively on Black designers, and the first in more than 20 years to have a menswear theme. “I want it to feel like the most epic night of power, a reflection of Black resiliency in a world that continues to be colonized, by which I mean policies and legislation that are nothing short of that,” he recently told Vogue. “It’s our turn.” Indeed. And welcome to the first Monday in May. How to watch the 2025 Met Gala Vogue will livestream the gala starting at 6 p.m. Eastern on Vogue.com, its YouTube channel and across its other digital platforms. Teyana Taylor, La La Anthony and Ego Nwodim will h…

Gen Alpha, the youngest generation of active consumers in the market, are teetering on the onset of teen angst. For many of them, an unavoidable trigger of it will be those pesky hormonal-triggered breakouts. It’s a moment for the skincare industry to once again swoop in and offer tweens and teens a smorgasbord of problem-skin creams, gels, patches and facemasks treatments. That part hasn’t changed for generations of consumers. What’s evolved are the strategies brands are using today to reach the youngest of them. Previous generations of teens, for instance, would see ads for acne brands in glossy magazines, newspaper inserts, on TV during Nickelodeon commercial b…

New Jersey Transit urged riders to reach their destinations before the end of the day Thursday or risk being stranded as last-minute talks continued in a bid to avert a rail strike by train engineers that would affect some 350,000 commuters in New Jersey and New York City. The labor dispute is stressing out some Manhattan commuters and already disrupting travel to Shakira concerts Thursday and Friday at MetLife Stadium in New Jersey. Amid the uncertainty over whether the strike would happen, the transit agency canceled train and bus service at the stadium. The system’s advisory provided riders with details on contingency plans that would take effect if engineers w…

MNTN Inc, the advertising technology company that counts Hollywood actor Ryan Reynolds as its chief creative officer, is expected to make its market debut on Thursday, in a closely watched initial public offering (IPO) that will test investor appetite for the rapidly growing segment of ad-supported streaming television. The Austin-based company priced shares at $16 on Wednesday, the higher end of its expected range, in an offering led by Morgan Stanley, Citigroup, and Evercore ISI. The stock will list on the New York Stock Exchange (NYSE) under the “MNTN” ticker symbol. Based on its IPO share price, MNTN—it’s pronounced Mountain—has an approximate valuation of $…

Noodles & Company, the fast-casual chain known for serving an array of noodle-based dishes, will shutter up to 21 restaurants. The brand, founded in Denver, Colorado in 1995, has already closed at least nine locations over the past year. In a conference call last week, chief financial officer Michael Hynes said, “We expect to close 13 to 17 company-owned and four franchise restaurants in 2025.” The most recent count is up from a previous estimate of 12 to 15 company-owned closures. Noodles & Company currently has 380 company-owned restaurants and 89 franchised locations in 31 states. According to the brand’s website, the impending closures are due to higher f…

Fabric and craft retailer Joann Inc. is officially shutting down all of its stores following a turbulent bankruptcy process. The company filed for Chapter 11 bankruptcy protection in January for the second time in less than a year, initially saying it would keep its stores open while restructuring its debt. However, just weeks after the filing, Joann reversed course and announced it would close 500 of its roughly 800 locations, as Fast Company reported. The closure of those stores was just the beginning. As part of the ongoing bankruptcy proceedings, Joann held an auction on February 21 to sell off its assets. A limited liability company called GA Joann Retail P…

The woman behind Instacart’s successful IPO, Fidji Simo, is joining OpenAI’s C-suite. On Wednesday, OpenAI CEO Sam Altman announced Simo’s new role as CEO of Applications. She will report directly to him after transitioning out of her current role at Instacart later this year. “In her new role, Fidji will focus on enabling our “traditional” company functions to scale as we enter a next phase of growth,” Altman said in a blog post. “Fidji brings a rare blend of leadership, product and operational expertise, and genuine commitment to ensuring our technology benefits everyone.” Before joining OpenAI’s executive team, Simo served as a member of its board of direct…

After Pope Francis’ funeral was held over the weekend, attention has now turned to the papal conclave to choose the next Pope. If you’re Catholic—or if you recently watched Conclave—you might be hedging your bets on who will next be seated at the Vatican. While the process usually happens behind closed doors, one TikTok user has created a “Fantasy Pope League,” in a similar style to fantasy football, an online game in which players collect points based on how real-life footballers perform each week, allowing people to play along at home and win points based off the real-life conclave. “There are ten times the number of people in this sweepstake as there are cardi…

Kelly Krasner was always interested in healthcare, but losing both parents to cancer when she was 24 reinforced what she thought would be a lifelong calling. After spending 13 years helping hospitals integrate more cancer screening and diagnosis technologies as a radiology sales and marketing director, Krasner spent six more working at various healthcare technology startups. When her company downsized and she lost her job in 2023, however, Krasner said it felt nearly impossible to get back into the industry. “I was applying and applying, and unfortunately—perhaps because of my age, my status, or people thinking I had to have a high title or a high income—I just wa…

A group backed by tech billionaires spent years and $800 million secretly buying up over 60,000 acres of land in Solano County, California, 60 miles northeast of San Francisco. The group—which calls itself California Forever and is funded by Marc Andreessen, LinkedIn cofounder Reid Hoffman, and Laurene Powell Jobs, among others—planned from the start to build a brand-new city for as many as 400,000 residents. But to do that they needed voter approval to change the county’s development rules. Just before heading to the ballot this past November, California Forever yanked its initiative despite spending over $9 million on its campaign. Now it seems California Forever ma…

Hawa Hassan was only 4-years-old when fighting forced her and her family from their home in Somalia. Hassan spent the next three years in Kenya, where some of her earliest memories were of running around tents in a refugee camp with her siblings and helping her mother stock the goods store she’d opened there. When she was seven, Hassan’s mother sent her to live with family friends in Seattle. It would be another 15 years before she saw her family again. “A lot of my childhood was spent wondering about my own background and my own identity,” said Hawa, a chef and entrepreneur who now lives in New York. “For many years, I had this deep desire to find people like mys…

Greg Creed spent 25 years at Yum Brands, including more than a decade in leadership roles at Taco Bell, before he retired from the company in 2020. He offered this unsolicited advice after a rough quarter for McDonald’s, in which same-store sales fell over 3%, the company’s worst drop since the pandemic. The problem, Creed asserts, is that McDonald’s isn’t chasing menu options that its customers will crave. And without a menu that elicits a strong reaction—either positive or negative—from diners, McDonald’s is just “being beige.” “Nothing as a brand is worse than being beige,” Creed wrote in a recent LinkedIn post. “It upsets no one, but let’s be honest: No one l…

As the 2025 Major League Baseball season gets into full swing, you’d expect the league to use its marketing muscle to hype the heroics of its biggest stars. But its anime-style ad campaign takes that idea to a new level. “Heroes of the Game” mixes the on-field superpowers of players like Shohei Ohtani, Paul Skenes, Julio Rodríguez, Juan Soto, and Aaron Judge with the pop cultural artistry of anime hits like One Piece and Fullmetal Alchemist. Created with ad agency Wieden+Kennedy, the league also partnered with Passion Pictures and Echelle Studios in Japan, as well as acclaimed animation director Hiroshi Shimizu, to make the work. The first ad features a whol…