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Changing an organism’s genome is a profound act, and the tools you use to make the changes don’t alleviate the need for responsible regulation. Since bursting onto the scene in 2012, CRISPR technology has been used to modify dozens of species from bacteria to livestock to plants, and even human embryos. Many countries have put ethical guardrails in place to prohibit creating designer babies. However, in agriculture, gene-edited crops are largely exempt from regulatory oversight, creating a “Wild West” where anything goes and edited crops are free to enter the food supply. Unlike “traditional” genetically modified organisms (GMO)—used since the 1990s to create Roun…

I slip on a pair of Nike running shoes. I clip a chunk of metal to the heel, which wraps around my lower leg like a shin guard. The battery goes on last, hugging it all like a high ankle bracelet. In all of 30 seconds, I’ve turned my legs into robots. I’m wearing Nike’s new exoskeleton footwear, dubbed Project Amplify. My legs feel heavier for sure. But with each step, there’s a little kick in my heel. Like a cherry bomb exploding underfoot. And when it launches next year under a new name for an undisclosed price, Project Amplify will power runs up to 10 kilometers long on a single charge, increasing your energy output by 15% to 20% along the way. “Think of i…

Below, Scott Anthony shares five key insights from his new book, Epic Disruptions: 11 Innovations That Shaped Our Modern World. Scott is a clinical professor of strategy at the Tuck School of Business at Dartmouth College. His research and teaching focus on the adaptive challenges of disruptive change. Previously, he spent over 20 years at Innosight, a growth strategy consultancy founded by Harvard Business School professor (and father of the idea of disruptive innovation) Clayton Christensen. What’s the big idea? In 1620, Sir Francis Bacon wrote that there were three technologies for which it was possible to draw a clear line before and after: the printing pre…

Most American cities have street networks that are engineered for us to comfortably drive much too fast for our surroundings. Even our old, pre-automobile cities have been “upgraded” to make dangerous driving habits easy. Transportation professionals are allowed to use good judgment when deciding how to design city streets, but they often need to be reminded, especially in cities where the state department of transportation has authority. It’s not enough for you as a good urbanist to tell an engineer to make better choices. After all, they’re not a malicious bunch trying to wreck society. They’re conforming to the long-established rules of the industry. The AA…

Grindr’s days as a public company could be numbered. The hookup and dating app, which went public via a SPAC merger in fall 2021, announced Tuesday that its largest shareholders, Raymond Zage and James Lu—who led the company’s go-public efforts—were exploring the possibility of acquiring Grindr’s outstanding stock, which would take the company private again. The confirmation of Lu and Zage’s goal of taking the company private followed reporting on Monday from Semafor, which outlined that a recent Grindr stock slide led a lender to seize shares that at least one of the men had used to back a personal loan. Semafor reported that the two were in talks with Fo…

I recently had an unsettling rideshare experience. Let me paint a visual picture. You have a Tesla doing its self-driving thing, a guy just sitting in the driver’s seat “supervising,” and a terrified human (me) in the backseat looking on in horror. Finally, I said, “Please keep your hands on the wheel when you’re driving me, OK?” Tesla’s autonomous functionality might be safe, but I don’t have enough trust yet to allow a Tesla to get me from Point A to Point B without a human steering it. There’s a parallel between self-driving cars and the current perceptions of AI and agents. You might be comfortable letting one of these automobiles make a simple right-hand …

Just a handful of years ago, the idea of one person creating a company worth over a billion dollars seemed like a pipe dream. Thanks to rapid advancements in AI, the possibility of a “solopreneur unicorn” is less a matter of “if” and more a matter of “when.” Earlier this year, OpenAI founder Sam Altman told Reddit cofounder Alexis Ohanian that his group chat of tech CEO friends have a betting pool for when the world will see a one-person billion-dollar company. Ten months later, some experts suggest that the company could be founded in 2026, if it hasn’t been already, due to rapid advancements in agentic AI. “The ability of a person to scale themselves, to automat…

Costco is famously adored by its fans, and its leadership wants the discount big-box chain to remain beloved. Costco co-founder and former CEO James Sinegal so fervently believes in keeping customers happy that he’s driven to profanity to express the strength of his feelings. “You can’t say ‘People are our most important product,’ and hang signs all over the place that say ‘People are our most important product,’ and then treat them like shit…. Your customers or your suppliers are going to see that you don’t really mean it,” he recently told an interviewer. Which is why a recent policy change by the retailer is so fascinating. Starting this month, Costco b…

Hello and welcome to Modern CEO! I’m Stephanie Mehta, CEO and chief content officer of Mansueto Ventures. Each week this newsletter explores inclusive approaches to leadership drawn from conversations with executives and entrepreneurs, and from the pages of Inc. and Fast Company. If you received this newsletter from a friend, you can sign up to get it yourself every Monday. When Mary Beth Laughton became president and CEO of Recreational Equipment, Inc. (REI) earlier this year, she inherited an organization with a rich heritage: REI was founded in 1938 by Lloyd and Mary Anderson, who joined some fellow outdoor enthusiast friends to buy ice axes that were only availabl…

Much like how the character Jack Dawson proudly proclaims to be king of the world after boarding the Titanic, film director James Cameron could claim to be king of the box office. Cameron chooses to take a mellower approach, letting the numbers do the talking. His latest film, Avatar: Fire and Ash, hits theaters this Friday and is primed to break even more box office records. Let’s take a look at the history of this franchise before we discuss industry projections. A brief history of the ‘Avatar’ films The first Avatar film came out in 2009 and received generally positive reviews. “Cameron and his artists have so lovingly imagined the moon of Pandora that…

A new study from scientists at the Centers for Disease Control and Prevention (CDC) shows that a dangerous strain of what some researchers have nicknamed a “superbug” is on the rise. The study, published on September 22 in the Annals of Internal Medicine, examines a bacteria called NDM-producing carbapenem-resistant Enterobacterales (NDM-CRE). Researchers found that, between 2019 and 2023, NDM-CRE infections surged by more than 460% in the U.S. These infections, which range from pneumonia to bloodstream and urinary tract infections, are extremely hard to treat and can be deadly due to their antibiotic-resistant properties—hence the name “superbug.” What is a “supe…

United Parcel Service posted third-quarter results that handily beat Wall Street’s expectations and gave details about its turnaround efforts, including approximately 48,000 job cuts. Shares rose more than 7% in afternoon trading on Tuesday. UPS earned $1.31 billion, or $1.55 per share, for the three months ended Sept. 30. The Atlanta-based company earned $1.99 billion, or $1.80 per share, a year earlier. Removing one-time costs, earnings were $1.74 per share. That easily topped the $1.31 per share that analyst polled by Zacks Investment Research were calling for. Revenue totaled $21.42 billion, surpassing Wall Street’s estimate of $20.84 billion. UPS …

Robert Redford’s legacy and mission were always going to be a key component of the 2026 Sundance Film Festival, which will be the last of its kind in Park City, Utah. But in the wake of his death in Septemberat age 89, those ideas took on a new significance. This January, the institute that Redford founded over 40 years ago, plans to honor his career and impact with and a screening of his first truly independent film, the 1969 sports drama “Downhill Racer,” and a series of legacy screenings of restored Sundance gems from “Little Miss Sunshine” to “House Party,” festival organizers said Tuesday. “As we were thinking about how best to honor Mr. Redford’s legacy, it’…

OpenAI has released a new web browser, the company’s latest bid to become consumers’ chief gateway to the web. The new browser, called ChatGPT Atlas, will initially be available on macOS on the desktop. Versions for Windows, iOS, and Android are coming soon, OpenAI says. OpenAI worked hard to build as many AI-driven features into Atlas as possible. For example, Atlas learns the user’s browsing history and, in some cases, can make content suggestions proactively. OpenAI CEO Sam Altman suggested that this first version of the browser is just the start, pledging to add “way more stuff that we will tell you about later” and adding that the company “can take thi…

If you’re an entrepreneur, at the end of the year you’re probably excited about the prospect of time off, but also daunted by the new year’s potential and all the deadlines you should be setting. Traditional planning methods like to-do lists and calendars are no longer enough for the complexity of modern careers and lives. This year, I leaned into AI to approach planning differently. When used thoughtfully, AI becomes a partner in strategy, and a system that helps you transform aspirations into structured, executable plans. Here’s how I recommend using AI to clarify where you’re headed and offer more clarity on how to get there. Redefine the role of AI …

OpenAI is going house hunting. The world-leading AI company is reportedly looking for a massive corporate campus of at least 500,000 square feet to house its ever-growing workforce of insanely well paid engineers and support staff. What’s more important than OpenAI’s desire to expand, though, is the company’s choice of where to do it. OpenAI is looking not in the trendy, vibrant heart of San Francisco, but deep in the dull, gray corporate expanses of Silicon Valley. That bucks a major trend in the AI space—and signals a broad and impactful change to the industry. Corporate hermit crabs For generations, America’s most successful tech companies …

The Coca-Cola Co. said sales of premium beverages and mini cans helped boost its third-quarter results despite tepid demand in the U.S. and elsewhere. The Atlanta beverage giant said Tuesday it continues to see a divergence among consumers in North America and Europe, with higher-income buyers opting for its more expensive brands like Smartwater, Topo Chico, and Fairlife, while middle- and lower-income consumers are under more pressure. Henrique Braun, Coke’s chief operating officer, said the company has focused on affordability by shrinking package sizes and leaning into sales of mini cans. Earlier this month, Coke announced it will sell individual, 7.5-ounce min…

Silicon Valley chipmaker Nvidia plans to supply hundreds of thousands of its graphics processing units for projects with South Korean businesses and the government to advance the country’s artificial intelligence infrastructure and technologies. The plan was announced Friday by the government, Nvidia, and some of South Korea’s biggest companies, including chipmakers Samsung Electronics, SK Hynix and auto giant Hyundai Motor, after President Lee Jae Myung met with Nvidia CEO Jensen Huang. At a news conference, Huang said he hopes to export Nvidia’s most advanced AI chips to China, following U.S. President Donald The President’s talks with Chinese President Xi Jinping on …

Before I was ever involved in the flower business, I jumped from job to job, trying to figure out where I belonged. I grew up in South Queens, New York, where the role models on my block were police officers and firemen who showed up when others needed them most. Naturally, I thought I’d follow that path and become a cop. That dream shifted into social work, a field that fed my heart but not my wallet. To make ends meet, I took on whatever work I could, flipping houses, tending bar, you name it. Through it all, I never forgot what my dad, a painting contractor, used to tell me: “If you’re old enough to walk, you’re old enough to work.” On paper, none of this looke…

The governor of Niigata on Tuesday formally gave local consent to put two reactors at the Kashiwazaki-Kariwa nuclear power plant in the north-central prefecture back online, clearing a last hurdle toward restarting the plant idled for more than a decade following the 2011 meltdowns at another plant managed by the same utility. Gov. Hideyo Hanazumi, in his meeting with Economy and Industry Minister Ryosei Akazawa, conveyed the prefecture’s “endorsement” to restart the No. 6 and No. 7 reactors at the Kashiwazaki-Kariwa plant, accepting the government’s pledge to ensure safety, emergency response and understanding of the residents. Restart preparations for No. 6 reac…

Many people spend an incredible amount of time worrying about how to be more successful in life. But what if that’s the wrong question? What if the real struggle for lots of us isn’t how to be successful, but how to actually feel successful? That’s the issue lots of strivers truly face, according to ex-Googler turned neuroscientist and author Anne-Laure Le Cunff. In her book Tiny Experiments, she explores how to get off the treadmill of constantly chasing the next milestone, and instead find joy in the process of growth and uncertainty. “You’re probably doing better than you give yourself credit for,” she explained on LinkedIn recently, before offering 10 telltal…