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Unlocking the power of genetics to provide meaningful answers to patients when they matter most is at the crux of precision diagnostics. As technologies advance, costs fall, and evidence builds, genomic sequencing has great potential to transform the trajectory of patient care. It will do so by shortening the diagnostic odyssey. It will guide and speed up more personalized and effective treatment decisions. And it will improve patient outcomes more than ever before. For innovation to truly scale, it will require deep collaboration and seamless integration across the healthcare ecosystem. BUILD A STRONGER PARTNERSHIP ECOSYSTEM Making genomic sequencing a standard pr…

Want more housing market stories from Lance Lambert’s ResiClub in your inbox? Subscribe to the ResiClub newsletter. Just 10 days ago, on February 10, Japan-based Sumitomo Forestry announced that it had agreed to acquire Tri Pointe Homes—a large U.S. homebuilder ranked No. 715 on the Fortune 1000—for $4.5 billion, signaling that Japanese builders were further accelerating their buying spree of U.S. homebuilders. Fast-forward to today, and Stanley Martin Homes—which has been owned by Japan-based Daiwa House since 2017—announced that it has agreed to buy United Homes Group, which has a strong presence in the Carolinas, for $221 million—further accelerating Japanese b…

The Epstein Files are dominating nightly news broadcasts and newspaper front pages. But in the media ecosystem there’s another format that’s proving a massive draw to news consumers: a podcast run by a non-journalist and entirely generated by AI. The Epstein Files is an investigative documentary podcast that, at the time of writing, has published 97 episodes—new episodes get uploaded twice daily—and notched up more than 700,000 downloads in a matter of days. That puts it in the top 10 rankings of podcast series on Apple Podcasts, and in the top 30 on Spotify. But it’s created by Adam Levy, an entrepreneur with a background in building data products and content creatio…

As built-in AI pops up in more aspects of everyday life, laymen are counting on the experts to keep technology safe to use. But one Meta employee’s misadventure with AI has social media users fearful for the future of AI alignment. Summer Yue is the director of alignment at Meta Superintelligence Labs, the company’s AI research and development division. Her LinkedIn bio states that she’s “passionate about ensuring powerful AIs are aligned with human values and guided by a deep understanding of their risks.” If anyone would have a handle on keeping AI in check, it’s Yue—and yet, on February 22, she posted about losing control of AI on her own computer. In a pos…

The advice you get early in your career can disproportionately shape your future. I can recall two or three conversations from when I was a college kid who liked writing that melted away ambiguity and set my vague ambitions on a path into the fog like a compass. For the latest release by The Steve Jobs Archive, the group is making the advice of some of the most uniquely impactful people in the world available to everyone. Given that Jobs did not own many physical objects, the archive has served as more of a repository of ideas for the next generation to think different. Each year, the Archive takes on SJA Fellows. And each year, it gives these fellows a book of l…

Ford is recalling nearly 413,000 Explorer SUVs in the U.S. The recall comes after federal regulators warned that a faulty rear suspension component called a “toe link” could restrict a driver’s steering control. According to a National Highway Traffic Safety Administration recall report, the recall impacts 2017-2019 Explorer vehicles, with the company estimated around 1% of the selected models are affected. The notice also explained that the recall is an expansion of previous NHTSA recall, number 21V537. “The root cause has not been fully determined to date,” a Feb. 20 report explained. “Some reports indicate vehicles experienced a seized CABJ”, which “will resu…

Dark Sky was a rarity in the app world. Universally beloved, the weather app had an uncanny ability to tell you when to expect rain, down to the minute. So when Apple announced plans to buy it six years ago, there was a collective sigh of frustration. The Android version, of course, disappeared almost immediately, while the iOS version was folded into Apple’s native Weather app. (The standalone iPhone app was discontinued.) The integration was never quite the same, though, and it seemed as if the magic of Dark Sky was lost. Now, however, the team behind the app is hoping lightning strikes twice. The developers of Dark Sky have announced a new iPhone app called Acm…

Meatball fans beware: A nationwide recall is underway for a popular brand of frozen meatballs sold at Aldi. The recall is due to the possibility that the product may contain metal fragments, which could cause serious injury if consumed. Here’s what you need to know. What’s happened? On Sunday, the U.S. Food Safety and Inspection Service (FSIS) posted a safety alert about a Class 1 recall—the highest possible designation the agency assigns to recalled products. A Class 1 recall means that there is “a health hazard situation where there is a reasonable probability that use of the product will cause serious, adverse health consequences or death,” according to the…

“I want a space odyssey. I wanted Star Wars. I got close to that once.” That’s production designer Hannah Beachler, talking about the grand filmic world she wants to build next. For our February episode of By Design, we spoke to Beachler (Creed, Black Panther) about her latest work with director Ryan Coogler on Sinners—the most Oscar-nominated film of all time. We caught up with her last time before she bagged an Oscar on Black Panther and then designed the sequel. https://statics.teams.cdn.office.net/evergreen-assets/safelinks/2/atp-safelinks.html She’s up for her second Academy Award for production design on Sinners next month, and she shared the pai…

Last October, 35 major donor families, calling their collaborative The Audacious Project, gathered in California and committed $1.03 billion to more than a dozen nonprofits whose proposed projects span multiple years and take on major challenges. The collaborative, housed at TED, announced the winning nonprofits Tuesday, after spending more than a year selecting the groups and helping them sharpen pitches for larger projects than philanthropic funders typically support. It’s not until the donors meet in person that they decide how much to give to each group. Jennifer Loving, the CEO of the San Jose-based nonprofit Destination: Home, said it was “shock and awe,” when the…

Home Depot’s fourth-quarter performance was muted by ongoing caution from American consumers in a weak housing market, but the home improvement retailer topped Wall Street expectations. The Atlanta company earned $2.57 billion, or $2.58 per share, for the three months ended Feb. 1. Stripping out one-time charges or benefits, earnings were $2.72 per share, topping analyst projections for per-share earnings of $2.53, according to FactSet. A year earlier it earned $3 billion, or $3.02 per share. An extra week in fiscal 2024 added approximately 30 cents per share to the year-ago quarter. Home Depot’s stock rose more than 3% before the market opened on Tuesday. Revenue to…

Throughout Kim Kardashian’s two-decade career in the public eye, the reality TV star’s entrepreneurial endeavors have included shapewear clothing brand Skims, makeup brand KKW Beauty, cofounding a private equity firm, and a super popular mobile game. But with her latest venture, Kardashian is stretching her mogul credentials into beverages, which has been familiar terrain for celebrities. She has become a “cofounder” of the energy drink company called Update. Though the startup has existed for four years—meaning Kardashian wasn’t a day-one founder—Update’s CEO and cofounder Daniel Solomons tells Fast Company that she has been a steady customer since 2023 and two years…

You’re invited to a holiday party with a dress code—cocktail attire. Instead of panic-scrolling through a bunch of dresses that look great on someone else and questionable on you, you open your laptop. A runway show starts in your living room. The lighting is cinematic. The music hits. And every model walking the runway is YOU. Same body, same proportions, same posture. You toggle the scene from dramatic spotlights to natural daylight to a candlelit restaurant, watching how each dress moves and fits in real life before you pick the one that feels right. But this isn’t just a better shopping experience; it is a design process that’s likely to yield an outfit that appea…

In medicine, “rare” is often used to describe conditions that affect relatively few people. But when you work in healthcare long enough—especially at the very beginning of life—you realize rare diseases are not rare at all. As a neonatologist, I cared for newborns whose symptoms didn’t follow a familiar script. An infant struggling to breathe. A baby who couldn’t feed. A child whose development stalled without a clear explanation. In the NICU, there is no luxury of time. Families are desperate for answers, and clinicians are making high-stakes decisions with incomplete information. Too often, we treated what we could see while suspecting there was something deeper…

With uncertainty as the new norm, leaders are understandably searching for psychological anchors. They’re looking for ideas that can steady people and sustain energy through change. One of those anchors is hope. Across corporate mission statements, fresh publications from thought leaders, and HR manifestos, corporations have elevated hope from a state of being to a strategic imperative. But what happens when an emotion becomes a business model? How to define hope in an organizational context Psychologically, hope is a cognitive and motivational state defined by three elements: agency (belief in your capacity to shape outcomes), pathways (the ability to identify…

If you’re in the Northeast, there’s a good chance you’ll be hunkering down inside for a few days as a major snowstorm batters the East Coast. And if you have a flight to catch, well, there’s a high probability that it might not be taking off at all. Due to the blizzard, which is forecast to bring up to two feet of snow in some areas, thousands of flights have already been canceled or delayed. Here’s what you need to know if you have a flight to catch. Thousands of flights have already been canceled due to the snowstorm As of the time of this writing, 5,348 flights within, into, or out of the United States today have already been canceled, according to data…

Cheap tote bag collections everywhere just got an attachable clip-on upgrade. Snatch is a shoulder strap system designed to attach and detach to fabric surfaces without damaging them. The clips are comprised of three pieces of hardware—a button, slotted loop, and fastener—and they can give thin-handled tote bags new life with a wider, sturdier shoulder strap in just a few steps, exemplifying a simple and solutions-oriented Occam’s razor approach to product design. To assemble, you place fabric over the button piece and thread it through the aluminum slotted loop. The fastener holds it all into place, and the strap is then attached onto a g-hook on the slotted…

Hello and welcome to Modern CEO! I’m Stephanie Mehta, CEO and chief content officer of Mansueto Ventures. Each week this newsletter explores inclusive approaches to leadership drawn from conversations with executives and entrepreneurs, and from the pages of Inc.and Fast Company. If you received this newsletter from a friend, you can sign up to get it yourself every Monday morning. During Charles Giancarlo’s first all-hands meeting after becoming CEO of Pure Storage in 2017, an employee asked: “How long are we going to keep the name Pure Storage?” The question suggested that having “storage” in the company’s name limited the range of products and services it could offe…

Snapple might be gearing up for a long-awaited comeback by taking a page out of its ‘90s playbook. On February 18, Snapple’s parent company, Keurig Dr Pepper, announced that the beloved tea brand is unveiling a refreshed visual identity designed to “return the Snapple brand to icon-status.” The new look, which will roll out beginning this March, includes new graphics, a logo inspired by the brand’s ‘90s look, and an updated bottle design that hearkens back to its original glass packaging. At the same time, Keurig Dr Pepper told Fast Company that it’s reinvesting in marketing efforts for Snapple, including through an ongoing campaign focused on the drink’s hometown of …

Ghost jobs are postings for positions that don’t actually exist for various reasons, and they waste countless hours for job seekers who apply to roles that were never meant to be filled. Experts in recruiting and career strategy have identified specific warning signs that reveal when a posting is likely fake or abandoned. This guide breaks down how to recognize these red flags before investing time in an application, so you can better focus your efforts on genuine opportunities. Prioritize Responsive Employers that Show Immediate Engagement One reliable way to identify a ghost job is to see whether applying to it leads to any human response at all. Today, silence h…

New York City is a city of walkers. More trips are made on foot than by car (41% versus 28%) and the city’s “80X50” climate action plan envisions that 80% of all trips by 2050 will be made either on foot, by biking, or by public transit. The problem is that pedestrian movement in the city has remained largely unmapped and underestimated—until now. Together with a team of researchers, Andres Sevtsuk, an associate professor in MIT’s Department of Urban Studies and Planning, has built what he says is the first complete model of pedestrian activity in New York City—and it’s a model that can now be applied to any U.S. city. The model, which maps foot traffic across al…

After officials released millions of pages of documents related to the late sex offender Jeffrey Epstein, revelations in his emails and other files have led to the resignations of multiple corporate executives, new investigations into abuses by Epstein and potential accomplices, and even the arrest of the United Kingdom’s former Prince Andrew. For those looking to research Epstein’s vast correspondence and web of connections across industry, government, and academia, some of the most effective tools have been built not by federal investigators or big-name news organizations but by a scrappy team of volunteer developers. Starting with a website called Jmail, which …