What's on Your Mind?

Fast-food companies, beware: Gas stations and convenience stores are coming for your customers. Fireside Market, a Wisconsin convenience store chain, announced a new store concept in Slinger, Wisconsin, designed to sell more burgers and less gas. It has a drive-through, curbside pickup area, and gourmet menu items—and it’s a model of the convenience store of the future. Fireside Market’s burger and sandwich menu is several steps up from the outdated idea of day-old taquitos spinning on a rotating food warmer at the local convenience store. Instead, its menu has items like a burger topped with bacon, pastrami, and balsamic-onion jam, and a grilled-salmon sandwich. …

The rise of artificial intelligence is transforming every industry, but it also creates enormous demand for digital infrastructure and natural resources. Data centers, the engines of this transformation, consume vast amounts of water and energy. A single hyperscale data center consumes up to 5 million gallons of potable water every day. In Phoenix, 58 centers together demand more than 170 million gallons daily, enough to ​​serve up to several hundred thousand households. This is the internet’s hidden water footprint, amplified by AI, cloud computing, and data-heavy services. Training a single large AI model in a Microsoft data center can require about 185,000 ga…

We don’t fully understand human biology. Not proteins, or cells or tissues—and certainly not how they all interact in the dynamic systems that make up our body. I believe AI is the answer to that problem. It offers the promise of a step-change in data analysis and eventually will understand our bodies’ processes at a fundamental level. It will “solve” biology. But it can’t be done by generalist large language models (LLMs) like ChatGPT. We’re going to need domain-specific agentic software that plans, acts, and adapts. The sort of AI that can support us across messy, multimodal workflows inherent to biological research. This is how we unlock the medicines and treat…